macrophage colony-stimulating factor การใช้

Granulocyte - macrophage colony - stimulating factor ( gm - csf ) exists widely in the hematopoietic system , immune system and nervous system
The researchers also spliced a gene into the virus that makes it produce granulocyte - macrophage colony - stimulating factor , which induces the body ' s immune system to recognize and attack tumors infected by the virus
Cd 14 * monocytes or bone marrow derived hematopoietic progenitor cells cultured with granulocyte - macrophage colony - stimulating factor ( gm - csf ) and il - 4 differentiate into efficient apc with morphology and cell surface molecule expression typical of immature dc . it was demonstrated that a variety of factors ( such as lps , tnf - a , il - 1 , monocyte - conditioned medium , and cd40 receptor cross - linking ) induce the maturation of immature dc to mature dc that are much more potent in activating t cells by increasing the expression of costimulatory molecules and cytokines , promoting the migration of dc to draining lymph nodes , and down - regulating the capacity of dc to capture and process antigen